Why avoid chicken after vaccination

AviPro® Thymovac ad us. vet.
Veterinary drugs

Provet AG

Lyophilisate for use in drinking water for chickens.

ATCvet code:QI01AD04



1 dose contains:
Active ingredient:
Live Chicken Infectious Anaemia (CIA) virus, strain Cux-1:
104.5 - 105.5 GKID50*,
* GKID50 = 50% tissue culture infectious dose: the virus titer required at which 50% of the cells inoculated with the virus are infected.
Host system: embryonated SPF hen eggs.
Appearance: red-brown lyophilisate.

Technical information active ingredients (CliniPharm)

● Avian Infectious Anemia Virus

Target species


Properties / effects

The vaccine induces an active immune response against CAV (Chicken Anemia Virus) infection in breeding flocks and protects the offspring against virus shedding, vertical transmission to the egg and horizontal transmission via faeces by passive immunization.
The parent animals are vaccinated at a time when the disease can no longer develop. The aim of vaccination is still to transfer maternal antibodies to the offspring in order to protect them from infection (horizontal transmission) in the particularly endangered first weeks of life.


For the active immunization of broiler chickens to protect against excretion of the hen anemia virus and to protect against transmission of the virus to the egg.
The following applies to active immunization:
Onset of immunity: 4 weeks after vaccination.
Duration of immunity: 43 weeks (determined by test infection).
For passive protection of the offspring against clinical symptoms and lesions of chicken anemia. Resilient protection of day-old chicks by maternal antibodies has been proven up to 51 weeks after vaccination of the parent animals and the chicks are protected on the first day of life.
1 dose per chicken (104.5 - 105.5 GKID50) to be administered.
For use in drinking water after resuspension.
The vaccination takes place once from the age of 8 weeks, but no later than 6 weeks before the start of laying.

Dosage and application

Administration in drinking water
1.The required number of vaccine doses and the amount of water should be determined (see below). Use the entire contents of the vaccine bottles for one stall or one drinking system only, splitting them up can lead to dosing errors.
2.All equipment used for vaccination (lines, hoses, drinking troughs, etc.) should be thoroughly cleaned and free of cleaning and disinfectant residues.
3.Only cold, preferably non-chlorinated, drinking water quality may be used. Adding skimmed milk powder (2 - 4 g / l water) or skimmed milk (20 - 40 ml / l water) can have a positive effect on the stability of the vaccine. The skimmed milk powder (<1% fat) or skimmed milk must be carefully mixed with the water at least 10 minutes before the vaccine is dissolved.
4.Remove the aluminum cover. Open the stopper of the vaccine bottle under water and transfer the contents completely into the vaccine solution by rinsing several times.
5.The drinking water system should be empty before vaccination. Residual water must be drained from the drinking lines as far as possible before the vaccine suspension is used.
6.The vaccine must be consumed within 2 hours. As the drinking behavior of chickens varies, it may be necessary to withdraw the drinking water 2-3 hours before vaccination to ensure that all birds are drinking during the vaccination phase. Each animal must receive an appropriate dose of the vaccine.
7.Each animal is to be given 1 dose by means of a single vaccination. The amount of water must be such that it is consumed by the animals within 2 hours. The diluted vaccine solution is added to cold, fresh water so that, as a rule of thumb, 1000 vaccine doses are dissolved in 20-40 liters for 1000 chickens. In case of doubt, the water intake must be determined the day before vaccination.
-When using proportional dispensers, a correspondingly higher concentrated stock solution must be prepared.
-Administer the ready-to-use vaccine immediately after reconstitution.
-During the drinking water vaccination, the animals must not have access to other water sources.
Read the package insert carefully before use to ensure that all animals receive the correct dose. An underdose
can lead to poor immunity training.

Application restrictions

Clinically ill animals must not be vaccinated.

unwanted effects

VetVigilance:Make a vaccinovigilance report
Zero days.

Other notes

Instructions for correct use

Do not use in chickens during the laying period and within 6 weeks before the beginning of the laying period.
Avoid stress before, during and after vaccination.
Use the entire contents of the opened container at once.

Special storage advice:

Keep medicines out of the reach of children.
Store in the refrigerator (2 ° C - 8 ° C)!
Do not expose to direct sunlight! Do not freeze!
Do not use the medicine after the expiry date which is stated on the container.
Shelf life after dissolution or reconstitution according to instructions: 2 hours.
Protect the ready-to-use vaccine suspension from direct sunlight and heat above 25 ° C as well as from frost!

Special warnings:

Special precautionary measures for use in animals
The vaccination takes place once from the age of 8 weeks of age, but no later than 6 weeks before the start of laying, in order to ensure protective immunity before the onset of the laying period.
The vaccine can pass to unvaccinated chickens because the vaccine strain is excreted in the faeces for at least 14 days after vaccination. Since the vaccine virus can cause clinical symptoms in day-old chicks without antibodies, transmission to unprotected chicks should be avoided. The transmission to chickens in the laying period or shortly before the beginning of the laying period as well as to animals under 3 weeks of age should be avoided. The vaccine should not be used in chicken flocks with mixed age groups.
Do not use in chickens during the laying period and within
6 weeks before the start of the laying period.
The vaccine can take between 7 and 49 days after vaccination in different
Organs and tissues are found.
No side effects were observed after administration of a 10-fold overdose.
In order to reduce the infection pressure before the onset of immunity, the litter should be removed and the house cleaned between runs in the rearing.
Special precautionary measures for the user
The vaccine contains live virus; any contamination by splashing or spilling must be avoided (e.g. wearing gloves and protective goggles, washing and disinfecting hands and equipment, etc.). Exercise caution when handling the faeces of vaccinated chickens as the virus can be shed for at least 14 days.
Wash and disinfect hands and equipment after use. There is no information on the safety and effectiveness of using this vaccine at the same time as any other. A decision to use this vaccine before or after other veterinary medicinal products must be made on a case-by-case basis.
Do not mix with other vaccines, immunological products or veterinary medicinal products.

Take special precautions for the disposal of any unused medicinal product or waste materials, if necessary

Waste material must be destroyed by autoclaving or immersion in a disinfectant approved by the competent authority.


Pack sizes:

Pack of 1 or 10 glass bottles with 500, 1000, 2500, 5000, 10000 vaccination doses.
The glass bottles (type I) are closed with chlorobutyl elastomer stoppers and aluminum caps.

Submission category: B



Lohmann Animal Health GmbH & Co. KG
Heinz-Lohmann-Str. 4 - 27472 Cuxhaven - Germany

IVI No. 1361

Information booth: 03/2007

This text has been approved by the authorities.