Can end-stage kidney failure be cured

Kidney weakness (acute): prognosis & prevention

Course & prognosis

Acute kidney failure usually has four stages:

Damage phase (initial phase)

This phase lasts from a few hours to days.

Oligo- / anuric phase

The urine excretion decreases significantly, so that the water and salt balance is disturbed. This phase lasts between two days and nine weeks, but it usually lasts ten days.

Recovery phase

The kidneys recover and produce increasing amounts of urine of up to five liters and more per day. The recovery phase takes about three to twelve weeks.

Recovery phase

The kidney cells become more or less functional again. The kidneys do not always heal completely. This phase can last up to two years.

The course of acute kidney failure depends on the underlying cause and the severity of the accompanying underlying diseases. In addition, early detection and treatment improves the success of the treatment. If the urine output is preserved, the prognosis is significantly better than if the urine output is absent.

Even with rapid treatment, acute kidney weakness is still fatal in almost every second person affected. Usually, however, the actual cause of death is not the weak kidneys, but the triggering, often severe, underlying disease, e.g. a shock in sepsis or an acute heart attack. If other organs are additionally damaged, this also worsens the prognosis. The most common cause of death are infections, as the disease makes the body particularly susceptible to pathogens.

In many cases, kidney function recovers after acute kidney weakness. Especially when fluid or blood loss, low blood pressure, or toxins have been treated successfully, the kidneys can get back to work.

Sometimes, however, acute kidney weakness develops into chronic kidney failure with damage that cannot be reversed. This is mostly the case with diseases and inflammations of the kidney corpuscles (glomeruli). 10-15% of patients require permanent renal replacement therapy.

Prevention & protection

Patients with existing kidney disease and impaired kidney function are particularly at risk of kidney failure. Before taking any drugs that can damage the kidneys (such as certain antibiotics, contrast agents, and pain relievers), be sure to tell your doctor about a known kidney disease. If their use cannot be avoided, drink enough.